The treaty seeks to give the global health body overarching powers during public health crises, bypassing national sovereignty.

The Republican governor blasted the agreement on May 23 during a press conference in the city of Cape Coral. He said: "There is no way that we in Florida will ever support this WHO thing. That's not going to happen. No way."

"You saw a lot of these elites advocate very pernicious policies. Part of the reason people want to move [to Florida] is because we rejected those policies. But they advocated very pernicious policies, including locking kids out of school."

DeSantis' remarks came amid a push by the Biden administration to give up the nation's sovereignty in times of global health crises, such as pandemics. A proposed revision of Article 9 of the International Health Regulations (IHR) of 2005, coming from the Biden administration, removes the requirement for the WHO to "consult with and attempt to obtain verification from" an affected country.

The revised IHR also removes every subsequent reference to consult with the relevant state party. This effectively gives the WHO blanket power to declare outbreaks without the need to consult with the relevant health authorities of different countries.