What caused the wreckage was the application of political force that was baked into the pandemic response this time in a way that has no precedent in human history. 

The response relied on compulsion imposed by all levels of government. The policies in turn energized a populist movement, Covid Red Guard that became a civilian enforcement arm. They policed the grocery aisles to upbraid the maskless. Drones swarmed the skies looking for parties to rat out and shut down. A blood lust against non compliers came to be unleashed at all levels of society. 

Lockdowns granted some people meaning and purpose, the way war does for some people. The compulsion to bludgeon others trickled down from government to the people. Madness overtook rationality. Once this took place, there was no longer a question of "Two weeks to flatten the curve." The mania to suppress the virus by ending person-to-person contact extended to two years.