Florida Gov. Ron DeSantis is on a collision course with one of the state's biggest industries over a law he signed banning businesses from asking customers whether they've been vaccinated against Covid-19.

Cruise ship operators, who sail out of Florida's large southern ports, say the order will make it make it harder for them to safely return to the seas, possibly imperiling a major economic driver in the state.

The GOP, under the influence of former President Donald Trump, has pursued cultural fights that roil its base at the expense of traditional conservative values, like free-market capitalism, with DeSantis, who is considering a presidential bid in 2024, and others picking fights with companies that they say undermine American values.

The Centers for Disease Control and Prevention gave the go-ahead Wednesday to begin work toward restarting cruises for the first time in over a year after the massive ships became some of the first superspreader locations for the coronavirus.