n order to fix this, Sharpe and his team thought that it could be useful to mobilize stem cells in the dental pulp and boost the natural healing abilities of teeth. Their work was built on top of earlier research, where it was demonstrated that the Wnt signaling pathway ?" an evolutionarily conserved pathway that regulates certain aspects of cell fate determination, cell migration, and cell polarity, among other things ?" was essential both for tissue repair and stem cell development in other parts of the body like the skin, brain, and intestines.