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IPFS News Link • Health and Physical Fitness

Even More Health Benefits of Niacinamide

•, By Dr. Joseph Mercola

Here, I'll review several additional conditions that can be prevented and/or treated with this inexpensive and readily available supplement.

More Niacinamide Is NOT Better, There's a Goldilocks' Dose

Keep in mind that the dosages used in the research studies discussed below do vary widely, but as a rule, I only recommend taking small doses of 50 milligrams of niacinamide three times a day.

This dosage has been shown to optimize energy metabolism and boost NAD+ levels, which are foundational for everything else to work. It can be taken four times a day if you space them out. Take a dose as soon as you get up, before going to bed, and twice evenly spaced between those times.

The problem with taking too much vitamin B3, whether in the form of niacin or niacinamide, is that it might backfire and contribute to cardiovascular disease as documented by the Cleveland Clinic. ZeroHedge reports:1

"The new study out of the Cleveland Clinic, published in Nature Medicine,2 determined there is a delicate balance between too much niacin and just enough — a sort of Goldilocks effect … [As] observed by the Cleveland Clinic team, too much niacin creates a byproduct known as 4PY.

This product circulates within the bloodstream and is associated with a higher risk of heart attack, stroke, and other cardiac events. Additionally, 4PY was shown in preclinical studies to trigger vascular inflammation, damaging blood vessels and eventually leading to atherosclerosis.