The three met with reporters Wednesday from inside a germ-free glassed-in room, hours before they were to blast off on Thursday morning.
"First of all, we need to arrange our home in the core module, then get started on a whole range of diagnostic tests on crucial technology and experiments," said mission commander Nie Haisheng, 56, the most senior of the three who is making his third trip to space.
"The task is very arduous and there are many challenges. My colleagues and I will cooperate closely, operate carefully and overcome all difficulties," Nie said.
Unsurprisingly, all said they had complete confidence in the mission, which carries special political meaning for the ruling Communist Party as it prepares to celebrate its centenary next month.