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IPFS News Link • Health and Physical Fitness

Coffee Linked To Reduced Parkinson's Risk

•, by George Citroner

New evidence suggests that the caffeine in your brew could pack an extra punch by reducing your risk of developing Parkinson's disease.

Findings Suggest Caffeine May Reduce Parkinson's Risk by 40 Percent

While previous research highlighted caffeine's benefits like increased energy and enhanced cognitive performance, a recent study in Neurology adds to the evidence that caffeine may help prevent Parkinson's disease, a progressive movement disorder.

The new study examined coffee intake and future Parkinson's risk in 184,024 participants across six European countries.

Unlike prior studies, it quantified caffeine biomarkers years before Parkinson's onset. Researchers identified 351 Parkinson's cases, matched with controls by age, sex, study center, and fasting status during blood collection.

Results showed that higher caffeine consumption and the presence of key metabolites like paraxanthine and theophylline were linked to reduced Parkinson's risk.

Paraxanthine and theophylline have been shown to have antioxidant effects. Oxidative stress is believed to play a role in the neurodegeneration seen in Parkinson's, so compounds with antioxidant activity may help protect neurons from damage. Also, Parkinson's involves the death of dopamine neurons. Some research suggests paraxanthine and theophylline may increase dopamine receptor signaling, which could compensate for neuron loss.

The neuroprotective effects were exposure-dependent, with the highest consumption group having nearly 40 percent lower Parkinson's risk compared to non-coffee drinkers.

The "sweet spot of coffee consumption" is probably two to four cups per day, Dr. Jack Wolfson, a board-certified cardiologist in Scottsdale, Arizona, not associated with the study, told The Epoch Times. Above that amount, "there is probably not much benefit," he added.