Kennedy made the bombshell accusation about a murder that's sparked many conspiracy theories during an interview Sunday with John Catsimatidis on WABC 770 AM's "Cats Roundtable."

"There is overwhelming evidence that the CIA was involved in his murder. I think it's beyond a reasonable doubt at this point," Kennedy said of JFK's assassination in a motorcade in Dallas, Texas.

"The evidence is overwhelming that the CIA was involved in the murder, and in the cover-up."

Kennedy Jr. cited James Douglas book "JFK and the Unspeakable" as compiling the most evidence on the topic — and labeled denials of the CIA's role as a "60 year cover-up."  

The US government's official investigation, the Warren Commission Report, concluded that Lee Harvey Oswald acted alone in the fatal shooting, and that there was no credible evidence he was part of a conspiracy to assassinate the 35th president. The report was released Sept. 24, 1964.