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IPFS News Link • Vaccines and Vaccinations

'You Can't Make This Stuff Up': Anti-Fentanyl Vaccine Funded by Military Blocks Drug&#39

• By Michael Nevradakis, Ph.D.

Stanley Kubrick's "A Clockwork Orange" features an experimental treatment — the Ludovico Technique — used to change the behavior of a young man who was addicted to sex and violence.

Soon, we'll have a vaccine designed to change human behavior — in real life.

A team of nine researchers led by the University of Houston (UH) this week announced the development of an anti-fentanyl vaccine. The vaccine is designed to block fentanyl's ability to enter the brain — and thus block its ability to create a "high."

According to a study in the journal Pharmaceutics, the research team tested 60 rats, 28 of which received the three-dose regimen of the vaccine.

The researchers plan to start phase 1 trials of the vaccine on humans in 2023, according to the Daily Mail. They also will soon begin manufacturing clinical-grade vaccine.

The UH study "could have major implications for the nation's opioid epidemic by becoming a relapse prevention agent for people trying to quit using opioids," according to lead author Colin Haile, M.D., Ph.D., a research associate professor of psychology at UH and the Texas Institute for Measurement, Evaluation, and Statistics, and founding member of the university's Drug Discovery Institute.


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