The Biden administration on Wednesday announced a $3.2 billion deal to purchase 105 million doses of Pfizer's COVID-19 vaccine for a fall vaccination campaign, with options to buy up to 300 million doses.

The Biden administration on Wednesday announced a $3.2 billion deal to purchase 105 million doses of Pfizer's COVID-19 vaccine for a fall vaccination campaign, with options to buy up to 300 million doses.

The contract includes a combination of adult and pediatric doses, and supplies of a re-formulated booster shot that will contain the original Wuhan variant and BA.4 and BA.5 Omicron subvariants.

The U.S. Food and Drug Administration (FDA) on Thursday advised COVID-19 vaccine manufacturers to produce the updated booster vaccine — which has not yet undergone human clinical trials — for this fall.