Novak Djokovic has been deported from Australia after his lawyers failed to convince three senior judges of his right to stay in Melbourne earlier this morning. 

The Serb, who arrived at the airport less than three hours following the judges' ruling, left the country on an Emirates flight from Melbourne to Dubai shortly after 10.30pm local time (11.30am GMT) after he was spotted making his way through the departures lounge.

Chief Justice James Allsop, Justice Anthony Besanko and Justice David O'Callaghan unanimously decided Djokovic did not have grounds to dispute Immigration Minister Alex Hawke's deportation order early this morning. 

Mr Hawke wielded his discretionary power on Friday afternoon to cancel the world number one's visa and deport him, despite a court ruling last week in his favour, after the government's lawyers argued he'd become an 'icon' for anti-vaxxers. 

The 20-time Grand Slam champion said he was 'extremely disappointed' in the outcome of the case, but that he 'respected' the court's decision and would co-operate with authorities.

Immigration Minister Alex Hawke meanwhile said he 'welcomed' the court's decision to 'exercise my power to cancel Mr Djokovic's visa in the public interest'. 

Chief Justice James Allsop made clear Djokovic could not launch an official appeal against Mr Hawke's decision. Instead, he had the opportunity to have the judges review the order based on its merit and lawfulness.

Djokovic as a result will have to cover the costs of all legal fees in the case. 

Deportation orders typically come with a three-year ban on returning to Australia, though it has not yet been decided whether this will be applied in Djokovic's case.