The series addresses Epstein's alleged co-conspirator Ghislaine Maxwell, his links with billionaire Leslie Wexner, founder of the Victoria Secrets clothing line, and others, as well as the non-prosecution deal he was given.

The special followed on the heels of Netflix's release of "Jeffrey Epstein: Filthy Rich," a mini-series that draws on a book of the same name by James Patterson. 

Promotional material for "Who Killed Jeffery Epstein?" promises that:  "… exclusive interviews and in-depth investigations reveal new clues about his seedy underworld, privileged life and controversial death. The three-hour special looks to answer the questions surrounding the death of this enigmatic figure."  Netflix billed its series this way: "Stories from survivors fuel this docuseries examining how convicted sex offender Jeffrey Epstein used his wealth and power to carry out his abuses."