The scene from the 1992 movie features Trump telling Macaulay Culkin's character how to find the lobby in the Trump Hotel.
The reason behind the deletion of the scene is not known, with many on Twitter claiming it was a political decision.
"CBC TV in Canada has cut Donald Trump's Home Alone 2 cameo out of their broadcast," tweeted Ryan Fournier. "They're so triggered by him that they had to edit him out of the film. Absolutely pathetic."