Mario Lopez says he doesn't understand parents letting their children transition genders.

Lopez, 45, appeared on The Candace Owens Show last month, and the two spoke about what Owens described as a 'weird trend' coming out of Hollywood, citing Charlize Theron's upbringing of her seven-year-old daughter Jackson, who identifies as a transgender girl.

Theron, 43, in April told DailyMail.com that she is raising Jackson to be a girl based on the child's stated preference: 'I thought she was a boy, too, until she looked at me when she was three-years-old and said, "I am not a boy!"'

Owens shared her own personal experience with kids to illustrate her point.

'Even though I'm not a parent, I nannied for five years of my life and the things that come out of children's mouths - they say whatever in the moment, you don't know what they've seen on TV what got in there ear,' she said. 'I've had children say they were mermaids, I've had children say they could fly - and jump off a staircase and thank God I caught him, right, cause he thought he could be Superman.