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IPFS News Link • Drugs and Medications

New drug promises to reverse the progression of Multiple Sclerosis

• http://www.gizmag.com, By Loz Blain

Teams from UC Riverside and New York's Rockefeller University have both used the same compound, indazole chloride, to successfully reverse the progression of MS in mice. The drug appears to be able to stimulate the regeneration of the myelin sheath – the nerve pathway coating that is progressively destroyed as MS attacks the nervous system.

MS affects around 400,000 people in the United States alone, and some 2.5 million around the world, according to Healthline. It's a debilitating disease in which the body's immune system begins to attack its own nervous system, gradually breaking down the protective cover called the myelin sheath, which coats the axons of nerve fibers in the brain and spinal cord.

As this demyelination progresses, patients begin to slowly experience the breakdown of their nervous system – sensation, vision and motor control begin to slowly degenerate, and permanent paralysis can be the end result. It's a horrible sentence.


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