Can Genomics Blow Up the Clinical Trial?
• http://www.technologyreview.com, By Susan YoungA novel kind of clinical trial is set to test several new lung cancer drugs based on the molecular profiles of each participating patient’s tumor.
If successful, the trial could help bring cancer-genome-targeted medicines to patients more quickly than has been possible to date. Trials often only test one new drug at a time, and in cases when researchers do use genomic profiling to match a patient to a new treatment, they may struggle to find suitable candidates.
One of the great promises of genomic medicine is that doctors will be able to tailor treatments to an individual patient’s disease. In the case of cancer, patients could be given an effective drug from the get-go based on a tumor’s particular molecular disruptions instead of going through a trial-and-error process to find a drug that works.
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